Tuesday December 11th, 2012 – Day 2
Functional Studies of the Na/K ATPase – Structure/Function – David Goldstein
Genes and transgenic models in migraine:
Lessons for AHC? – Arn V.D. Maagdenberg
Structure, function, and biological roles of Na, K-ATPase isoforms in excitable tissues – Kathy Sweadner
Insights to disease mechanisms from structural studies of Na+, K+-ATPase and related ion pumps – Poul Nissen
Functional consequences of alpha-3 Na, K-ATPase mutations at the molecular and cellular levels- Bente Vilsen
Cell biological and mutational studies of Na, KATPase, insect cell expression system – Jan Koenderink
Functional and proteomic studies in platelets from AHC patients reveals a lysosomal granule defect – Michela Di Michele
Coffee and refreshments Functional Studies of the Na/K ATPase .Electro Physiology & in vivo work – Sophie Nicole
Electrophysiological studies in oocytes of disease mutations in atp1a2 and 3.- Thomas Friedrich
Electrophysiological studies in oocytes of Na, KATPase mechanisms – Hanne Poulsen
Electrophysiology of Na, K-ATPase – David Gadsby
Discussion
A Mouse Model for ATP1A3-related Alternating Hemiplegia of Childhood – Steven Clapcote
Zebrafish and mouse models of atp1a2 and atp1a3 – Karin Lykke-Hartmann
Mania-like behaviour induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump – Greer S. Kirshenbaum
Discussion Roundtable Discussion
Functional Biology of ATP1A3 and ATP1A3 Mutations – Moderators : Poul Nissen and Bente Vilsen
• Key challenges
• Directions moving forward
• Collaborative groupings
Roundtable Discussion
Collaborations and Funding
Moderators: Tsveta Schyns and David Goldstein
• Key challenges
• Directions moving forward
• Collaborative groupings
• Outcomes of the Symposium
Closing message from the AHC Community – Jeff Wuchich
End of the meeting